Protein Purification
MilliporeSigma™ Calbiochem™ VEGFR2 Kinase Inhibitor VI, Ki8751
The VEGFR2 Kinase Inhibitor VI, Ki8751, also referenced under CAS 228559-41-9, controls the biological activity of VEGFR2 Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ InSolution™ TAPI-1
InSolution™ TAPI-1, CAS 171235-71-5, is a 10mm solution of TAPI-1 in DMSO. A structural analog of TAPI-0 (Cat. No. 579050) with similar in vitro efficacy for the inhibition of MMPs and TACE.
MilliporeSigma™ Calbiochem™ Heat Shock Factor 1 Inhibitor, KRIBB11
The Heat Shock Factor 1 Inhibitor, KRIBB11 controls the biological activity of Heat Shock Factor 1.
MilliporeSigma™ Calbiochem™ Simvastatin
A lipophilic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that blocks Ras function through inhibition of farnesylation.
MilliporeSigma™ Calbiochem™ (--)-Nicotine, Ditartrate
Potent agonist of the nicotinic acetylcholine receptor.
MilliporeSigma™ Calbiochem™ mTOR Kinase Inhibitor II, WYE-354
The mTOR Kinase Inhibitor II, WYE-354, also referenced under CAS 1062169-56-5, controls the biological activity of mTOR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Spermidine, Trihydrochloride
Polyamine that plays an important role in the regulation of cellular proliferation and differentiation.
MilliporeSigma™ Calbiochem™ Sodium Orthovanadate
A broad spectrum potent inhibitor of protein tyrosine phosphatases.
MilliporeSigma™ Calbiochem™ GGTI-286
A potent, cell-permeable, and selective inhibitor of GGTase I.
MilliporeSigma™ Calbiochem™ Notch Transcription Factor Inhibitor, SAHM1
Notch Transcription Factor Inhibitor, SAHM1, is a cell-permeable inhibitor that prevents assembly in the NOTCH1 trans-activation complex.
MilliporeSigma™ Calbiochem™ RAD51-Stimulatory Compound-1, RS-1
A cell-permeable sulfonamido-benzamide-based allosteric regulator that stimulates DNA binding and recombinase activities of hRAD51 by locking hRAD51 in an active conformation without affecting its active site ATP hydrolysis.
MilliporeSigma™ Calbiochem™ Cdk1 Inhibitor IV, RO-3306
RO-3306 is a cell-permeable, potent and ATP-competitive inhibitor of Cdk1 (Ki = 35 nM and 110 nM for Cdk1/B1 and Cdk1/A, respectively).
MilliporeSigma™ Calbiochem™ α-Synuclein Blocker, ELN484228
A cell-permeable compound that reversibly binds to pocket I of the monomeric α-synuclein (α-syn) and reverses α-syn-induced impairment of phagocytosis in H4 neuroglioma cells.
MilliporeSigma™ Calbiochem™ InSolution™ Q-VD-OPh, Non-O-methylated
InSolution™ Q-VD-OPh, Non-O-methylated, is a cell-permeable, irreversible, broad-spectrum inhibitor of caspases (IC50 = 50, 100, 430, and <25 nM for caspase-1,-8, -9, and -3, respectively).
MilliporeSigma™ Calbiochem™ p21-Activated Kinase Inhibitor III, IPA-3
The p21-Activated Kinase Inhibitor III, IPA-3, also referenced under CAS 42521-82-4, controls the biological activity of p21-Activated Kinase. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.